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Research monkeys still having a ball days after busting out of lab, police say

If you need any inspiration for cutting loose and relaxing this weekend, look no further than a free-wheeling troop of monkeys that broke out of their South Carolina research facility Wednesday and, as of noon Friday, were still "playfully exploring" with their newfound freedom.

In an update Friday, the police department of Yemassee, SC said that the 43 young, female rhesus macaque monkeys are still staying around the perimeter of the Alpha Genesis Primate Research Facility. "The primates are exhibiting calm and playful behavior, which is a positive indication," the department noted.

The fun-loving furballs got free after a caretaker "failed to secure doors" at the facility.

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After decades, FDA finally moves to pull ineffective decongestant off shelves

In a long-sought move, the Food and Drug Administration on Thursday formally began the process of abandoning oral doses of a common over-the-counter decongestant, which the agency concluded last year is not effective at relieving stuffy noses.

Specifically, the FDA issued a proposed order to remove oral phenylephrine from the list of drugs that drugmakers can include in over-the-counter products—also known as the OTC monograph. Once removed, drug makers will no longer be able to include phenylephrine in products for the temporary relief of nasal congestion.

"It is the FDA’s role to ensure that drugs are safe and effective," Patrizia Cavazzoni, director of the FDA’s Center for Drug Evaluation and Research, said in a statement. "Based on our review of available data and consistent with the advice of the advisory committee, we are taking this next step in the process to propose removing oral phenylephrine because it is not effective as a nasal decongestant."

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What’s next for reproductive rights in the US

This article first appeared in The Checkup, MIT Technology Review’s weekly biotech newsletter. To receive it in your inbox every Thursday, and read articles like this first, sign up here.

Earlier this week, Americans cast their votes in a seminal presidential election. But it wasn’t just the future president of the US that was on the ballot. Ten states also voted on abortion rights.

Two years ago, the US Supreme Court overturned Roe v. Wade, a legal decision that protected the right to abortion. Since then, abortion bans have been enacted in multiple states, and millions of people in the US have lost access to local clinics.

Now, some states are voting to extend and protect access to abortion. This week, seven states voted in support of such measures. And voters in Missouri, a state that has long restricted access, have voted to overturn its ban.

It’s not all good news for proponents of reproductive rights—some states voted against abortion access. And questions remain over the impact of a second term under former president Donald Trump, who is set to return to the post in January.

Roe v. Wade, the legal decision that enshrined a constitutional right to abortion in the US in 1973, guaranteed the right to an abortion up to the point of fetal viability, which is generally considered to be around 24 weeks of pregnancy. It was overturned by the US Supreme Court in the summer of 2022.

Within 100 days of the decision, 13 states had enacted total bans on abortion from the moment of conception. Clinics in these states could no longer offer abortions. Other states also restricted abortion access. In that 100-day period, 66 of the 79 clinics across 15 states stopped offering abortion services, and 26 closed completely, according to research by the Guttmacher Institute.

The political backlash to the decision was intense. This week, abortion was on the ballot in 10 states: Arizona, Colorado, Florida, Maryland, Missouri, Montana, Nebraska, Nevada, New York, and South Dakota. And seven of them voted in support of abortion access.

The impact of these votes will vary by state. Abortion was already legal in Maryland, for example. But the new measures should make it more difficult for lawmakers to restrict reproductive rights in the future. In Arizona, abortions after 15 weeks had been banned since 2022. There, voters approved an amendment to the state constitution that will guarantee access to abortion until fetal viability.

Missouri was the first state to enact an abortion ban once Roe v. Wade was overturned. The state’s current Right to Life of the Unborn Child Act prohibits doctors from performing abortions unless there is a medical emergency. It has no exceptions for rape or incest. This week, the state voted to overturn that ban and protect access to abortion up to fetal viability. 

Not all states voted in support of reproductive rights. Amendments to expand access failed to garner enough support in Nebraska, South Dakota, and Florida. In Florida, for example, where abortions after six weeks of pregnancy are banned, an amendment to protect access until fetal viability got 57% of the vote, falling just short of the 60% the state required for it to pass.

It’s hard to predict how reproductive rights will fare over the course of a second Trump term. Trump himself has been inconsistent on the issue. During his first term, he installed members of the Supreme Court who helped overturn Roe v. Wade. During his most recent campaign he said that decisions on reproductive rights should be left to individual states.

Trump, himself a Florida resident, has refused to comment on how he voted in the state’s recent ballot question on abortion rights. When asked, he said that the reporter who posed the question “should just stop talking about that,” according to the Associated Press.

State decisions can affect reproductive rights beyond abortion access. Just look at Alabama. In February, the Alabama Supreme Court ruled that frozen embryos can be considered children under state law. Embryos are routinely cryopreserved in the course of in vitro fertilization treatment, and the ruling was considered likely to significantly restrict access to IVF in the state. (In March, the state passed another law protecting clinics from legal repercussions should they damage or destroy embryos during IVF procedures, but the status of embryos remains unchanged.)

The fertility treatment became a hot topic during this year’s campaign. In October, Trump bizarrely referred to himself as “the father of IVF.” That title is usually reserved for Robert Edwards, the British researcher who won the 2010 Nobel prize in physiology or medicine for developing the technology in the 1970s.

Whatever is in store for reproductive rights in the US in the coming months and years, all we’ve seen so far suggests that it’s likely to be a bumpy ride.


Now read the rest of The Checkup

Read more from MIT Technology Review’s archive

My colleague Rhiannon Williams reported on the immediate aftermath of the decision that reversed Roe v. Wade when it was announced a couple of years ago. 

The Alabama Supreme Court ruling on embryos could also affect the development of technologies designed to serve as “artificial wombs,” as Antonio Regalado explained at the time.

Other technologies are set to change the way we have babies. Some, which could lead to the creation of children with four parents or none at all, stand to transform our understanding of parenthood.  

We’ve also reported on attempts to create embryo-like structures using stem cells. These structures look like embryos but are created without eggs or sperm. There’s a “wild race” afoot to make these more like the real thing. But both scientific and ethical questions remain over how far we can—and—should go.

My colleagues have been exploring what the US election outcome might mean for climate policies. Senior climate editor James Temple writes that Trump’s victory is “a stunning setback for climate change.” And senior reporter Casey Crownhart explains how efforts including a trio of laws implemented by the Biden administration, which massively increased climate funding, could be undone.

From around the web

Donald Trump has said he’ll let Robert F. Kennedy Jr. “go wild on health.” Here’s where the former environmental lawyer and independent candidate—who has no medical or public health degrees—stands on vaccines, fluoride, and the Affordable Care Act. (New York Times)

Bird flu has been detected in pigs on a farm in Oregon. It’s a worrying development that virologists were dreading. (The Conversation)

And, in case you need it, here’s some lighter reading:

Scientists are sequencing the DNA of tiny marine plankton for the first time. (Come for the story of the scientific expedition; stay for the beautiful images of jellies and sea sapphires.) (The Guardian)

Dolphins are known to communicate with whistles and clicks. But scientists were surprised to find a “highly vocal” solitary dolphin in the Baltic Sea. They think the animal is engaging in “dolphin self-talk.” (Bioacoustics)

How much do you know about baby animals? Test your knowledge in this quiz. (National Geographic)

For fame or a death wish? Kids’ TikTok challenge injuries stump psychiatrists

Kids and teens can make some pretty hairbrained choices sometimes. But when a kid's choice is to engage in a TikTok challenge that threatens their life, psychiatrists can struggle to understand if it was just an exasperating poor choice born out of impulsivity and immaturity or something darker—an actual suicide attempt.

In a Viewpoint published today in JAMA Psychiatry, two psychiatrists from the University of Tennessee Health Science Center at Memphis raise the alarm about the dangers and complexities of TikTok challenges. They're an "emerging public health concern" for kids, the psychiatrists write, and they're blurring the lines between unintentional injuries and suicide attempts in children and teens.

The child and adolescent psychiatrists Onomeasike Ataga and Valerie Arnold say that their psychiatry team first saw injuries from TikTok challenges during the COVID-19 pandemic, but the trend has continued since the pandemic eased. Over recent years, they've seen children and teens hospitalized from a variety of challenges, including the "blackout challenge," in which participants attempt to choke themselves until they pass out; the "Benadryl challenge," in which participants ingest a large amount of the allergy medicine to get high and hallucinate; and the "fire challenge," in which participants pour a flammable liquid on their body and light it on fire. In these cases, the psychiatry team is sometimes called in to help assess whether the children and teens had an intent to self-harm. It's often hard to determine—and thus hard to decide on treatment recommendations.

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22 Great VR Games for Relaxation & Meditation on Quest, PC VR, and PSVR 2

In times like these it’s nice to be able to get away from it all, if only for a brief moment. If you have a VR headset you’re one of the lucky people who can enter other realities from the confines of your living room, so why not use it for your wellbeing? Here we’ve gathered Quest meditation games and experiences focused on VR relaxation. This list also covers apps on PC VR and PSVR 2, so there’s something for everyone.

Below you’ll find that we split up 20 VR meditation and relaxation experiences into several categories: Nature Relaxation, Musical Relaxation, Creation & Puzzling, Musical Creation, Meditation, Reflection, Mindfulness, and Exploration.

We’ve refreshed our list with a few new apps and the latest info. Here’s a quick summary of changes since the last update:

  • Added Earth Quest (Nature Relaxation section)
  • Added Squingle Mini (Creation & Puzzling section)
  • Added Cosmic Flow (Meditation section)
  • Prices, trailers, and platforms updated

Nature Relaxation

Ocean Rift (Quest, PC VR) – $10

Ocean Rift is like an aquarium where you get to swim around with the fish. You’ll get to see lovingly animated sea creatures up close and you might even learn a thing or two with more than 40 narrated points of interest to find. And if you’re on Quest 3, Ocean Rift has a mixed reality mode that lets you turn your own room into an aquarium.

Real VR Fishing (Quest) – $20

You can probably guess what this one is about… but you might not expect that the app has some rather beautiful environments. So yes, you’ll be fishing and you can take it as fast or as slow as you’d like. Consider putting on some music or even a podcast while you relax and wait for the big one. Real VR Fishing also supports multiplayer so you can fish with friends.

Google Earth VR (PC VR) – Free

Google Earth VR is exactly what it sounds like… its Google Earth, but in VR. Beyond being able to explore essentially the entire globe as if you were a giant towering over it, the app can also be a wonderful way to relax. Find yourself a pretty place (there’s some great ones in the ‘Featured’ section inside the app), bring yourself down to ground level, and simply sit as a giant and take in the scene around you. You can even set the mood by adjusting the time of day. It can also be magical to just ‘wander’ starting from a familiar place and see where you wind up. Considering both the quality of the experience and the fact that its free, this one is an absolute must-try.

EarthQuest (Quest) – $10

EarthQuest aims to not only bring the Google Earth VR experience to Quest, but modernize it too. EarthQuest adds multiplayer so you can explore the globe with friends as well as natural language input allowing you to ask ChatGPT to tell you more about the things you find.

Musical Relaxation

Tetris Effect: Connected (Quest, PC VRPSVR 2) – $30, $40

Tetris Effect is classic Tetris gameplay wrapped in an audio-visual experience which uniquely accompanies each of the game’s levels. As you maneuver the blocks you’ll hear sounds that fit into the beat. Don’t lose yourself too much in the sights and sounds though as some of the levels will take skill and practice to complete, even on ‘Normal’ difficulty. A post-launch update to the game has brought cross-platform multiplayer to Tetris Effect so you can vibe with friends no matter if they’re playing in VR or on a flat screen.

Sheaf – Together EP (SteamVR) – Free

Ever wish you could cruise down an endless highway, watching as the trees, buildings, and city streets pass you by while a synthwave soundtrack perfectly fits the vibe? Artist and musician Sheaf has created just that—a short VR experience which is hand-crafted to fit a three track synthwave album. For the great price of free, this one is a no-brainer.

Creation & Puzzling

Squingle Mini (Quest, $1) & Squingle (PC VR, $15)

Squingle is one of those games that you can look at and still not entirely understand what you’re actually seeing. But once you get your hands on the game all becomes clear: it’s a clever, trippy, and fun puzzle game that plays to VR’s spatial strengths. To put it simply, the goal of Squingle is to guide a pair of spinning balls through a pipe. Sounds easy enough, right? Well like any good puzzle game, Squingle starts simply enough but introduces more difficult concepts as you go—like a button that reverses the spin of the balls or one that changes the axis of the spin. And the pipe? It’s actually a bit more like a cosmic bowel that undulates with twists, turns, and parallel tunnels.

Read Our Hands-on

Puzzling Places (Quest, PSVR 2*) – $15, $20 (*free demo)

Puzzling Places is a series of 3D puzzles made out of 3D scans of real-life places. Going from flat jigsaw puzzles to 3D puzzles will stretch your brain in satisfying new ways as you use all your 2D jigsaw strategies (like sorting by color, edges, and the like) while leaning into your spatial reasoning sense to find the right connections between pieces. Even more satisfying—when you’re done you have a tiny 3D diorama to explore! Since launch, Puzzling Places has been updated with a multiplayer mode so you can relax and puzzle with friends, and mixed reality mode on Quest 3 so you can solve puzzles right in your room.

*Free Puzzling Places demo on PSVR 2

Vermillion (Quest, PC VR) – $20

Vermillion is a free-form painting app designed to replicate the oil medium. You can do everything from basic paint-by-number to completely freestyle painting with color mixing and the use of various brushes to achieve different effects. With a multiplayer mode up to four players total can paint together. You can also paint in your own space thanks to mixed reality on Quest 3, or even do co-located painting with a friend so you’re both painting in the same physical room.

Gadgeteer (Quest, PC VR) – $15

Have you ever wished you had a whole room and a box full of tracks, balls, and dominos to build the ultimate Rube Goldberg machine? You’re in luck. Gadgeteer will let you finally imagine your childhood dream of filling an entire room with a crazy chain-reaction-machine without the cat knocking everything over. Beyond being able to build whatever you want in ‘Sandbox Mode’, Gadgeteer is a full fledged puzzle game with 60 puzzles to complete and a pleasant soundtrack to boot.

Read Our Review

Cubism (Quest, PC VR) – $10

Cubism is a casual VR puzzle that plays a bit like a 3D version of Tetris. Its sleek, casual design makes it great for relaxing seated play. But fear not, while the puzzle concept is simple, Cubism will have you scratching your head in short order as difficulty increases across 60 stages. The bright, void-like environment makes it easy to forget about the woes of the real world as you focus on finding the right fit for the pieces before you to the backdrop of a beautiful piano soundtrack. Thanks to hand-tracking support, you can even play without needing to pick up your controllers. A post-launch update has added a mixed reality mode on Quest 3 so you can solve puzzles from the comfort of your own room.

Vrkshop (PC VR) – $20

Vrkshop describes itself as a “VR woodworking game” and aims to recreate a hands-on woodshop where you can measure, mark, cut, nail, and much more. With a realistic wood-cutting system, the app challenges you to use the tools at your disposal to create furniture and other objects with no explicit instructions.

Color Space (Quest) – $10

Color Space is a virtual reality coloring book where you get to bring life to a full 3D scene rather than just a flat page. Step into one of 26 environments and start adding color as you see fit. As you color the scene, it will start to come alive with animated elements and ambient sounds.

Musical Creation

Electronauts (QuestPC VR) – $20

Electronauts is like a VR DJ station with training wheels. Though you can take the training wheels off if you’re especially talented, the training wheels are actually part of the appeal; Electronauts does an incredible job of letting you express your inner musical creativity even if you don’t have instrumental talent. The game serves up some 80 tracks, each which function as a custom sound-kit with unique instruments, backing tracks, and more. And as a huge bonus, PC VR version of the game are multiplayer, meaning you can jam out with a friend. The track list is heavy on the EDM side (though there are some chill songs to be found) so if that’s not your cup of tea you might want to look elsewhere.

Read Our Review

Drops: Rhythm Garden (PC VR) – $7

Drops is a musically focused experience where shapes that you place make different sounds when struck with falling balls. With an endless flow of balls, you can construct a cacophony of sounds on the fly, adding new shapes and creating new paths as you go. Think of it like a Rube Goldberg machine, but for making minimal, meditative music.

Continue on Page 2: Meditation, Reflection, Mindfulness, and Exploration »

The post 22 Great VR Games for Relaxation & Meditation on Quest, PC VR, and PSVR 2 appeared first on Road to VR.

“Havard”-trained spa owner injected clients with bogus Botox, prosecutors say

A Massachusetts spa owner has been arrested for what prosecutors describe as a blundering scheme in which she conspicuously smuggled counterfeit Botox and skin fillers into the US, then peddled them to clients by falsely claiming to be a nurse with a degree from "Havard" [sic] and a license from the state's "Estate Board."

Nevertheless, the woman—Rebecca Fadanelli, 38, of Stoughton—allegedly performed over 2,700 illegal injections between 2021 and 2024, raking in over $900,000 with the scam.

According to an affidavit from a special agent with the Food and Drug Administration, Fadanelli was smuggling in counterfeit Botox and fillers from China and Brazil. Between November 2023 and March 2024, Customs and Border Protection (CBP) seized at least six parcels from China addressed to Fadanelli or her employees. The packages included various counterfeit injectable drugs, including products labeled as Botox and skin fillers Sculptra and Juvederm.

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Gut Bacteria Modulate Stress Responses Over Time

This shows a brain and bacteria.New research has unveiled how gut bacteria play a key role in regulating stress by interacting with circadian rhythms, opening possibilities for microbiome-based therapies for mental health. Researchers found that depletion of certain gut bacteria can lead to time-specific increases in stress responses through the HPA axis, the body's central stress response system. Specific bacteria, such as Limosilactobacillus reuteri, were identified as crucial to modulating stress hormones throughout the day.

Nodal connects hopeful parents with surrogates as reproductive freedom hangs in limbo

Many people who want to have children can’t, or shouldn’t, carry a pregnancy for a variety of reasons. Gestational surrogacy can be a great option for those individuals — if they can endure the lengthy wait times and afford to pay for the costly service. New York-based Nodal looks to make the process less expensive, […]

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And the winner of Startup Battlefield at Disrupt 2024 is . . . Salva Health

Over the last three days, 20 startups participated in the incredibly competitive Startup Battlefield at TechCrunch Disrupt. These 20 companies were selected as the best of the Startup Battlefield 200 and competed for a chance to take home the Startup Battlefield Cup and $100,000. After three days of intense pitching, we have a winner. The […]

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Slivered onions are likely cause of McDonald’s E. coli outbreak, CDC says

Slivered onions are the likely source of the multi-state E. coli outbreak linked to McDonald's Quarter Pounder burgers that continues to grow, the Centers for Disease Control and Prevention announced Wednesday.

Onions were one of two primary suspects when the CDC announced the outbreak on October 22, with the other being the beef patties used on the burgers. But onions quickly became the leading suspect. The day after the CDC's announcement, McDonald's onion supplier, Taylor Farms, recalled peeled and diced yellow onion products, and several other fast food chains took onions off the menu as a precaution. (No other restaurants have been linked to the outbreak to date.)

According to the CDC, traceback information and epidemiological data collected since then have all pointed to the onions, and, according to McDonald's, state and federal testing of the beef patties has all come back negative.

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Person accidentally poisoned 46 coworkers with toxin-loaded homemade lunch

For some, microwaving fish in the employee lunch room is the ultimate work faux pas. But for one (likely mortified) employee of a seafood distribution plant in Maryland, it's probably causing a mass poisoning with the homemade noodle dish they brought to share for lunch. The dish sickened 46 employees, spurring their employer to hastily release a statement assuring customers that it wasn't the company's food that caused the illnesses.

On October 21, first responders and paramedics arrived at the NAFCO Wholesale Fish Distribution Facility in Jessup, where dozens of employees had abruptly fallen ill about three hours after lunch. Helicopter footage of the event captured images of workers around picnic tables outside the plant, some doubled over and with their heads down.

Ultimately, 46 people were sickened, and at least 26 were treated at an area hospital with symptoms of food poisoning, according to The Baltimore Banner. They all recovered.

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2024 Startup Battlefield Top 5 Finalists: geCKo Materials

A bio-inspired Dry Adhesive that is ultra-strong, reusable, leaves no residue, and requires no force to detach. The product opens new applications in industrial automations, robotic gripping, space and defense. Subscribe for more on YouTube: https://tcrn.ch/youtube Follow TechCrunch on Instagram: http://tcrn.ch/instagram TikTok: https://tcrn.ch/tiktok X: tcrn.ch/x Threads: https://tcrn.ch/threads Facebook: https://tcrn.ch/facebook Bluesky: https://tcrn.ch/bluesky Mastodon: https://tcrn.ch/mstdn Read more: […]

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2024 Startup Battlefield Top 5 Finalists: MabLab

Maker of 5-in-1, at-home rapid tests to screen for laced drugs and spiked drinks. Results delivered in under three minutes, potentially saving over 100,000 lives annually and preventing an additional 5 million hospitalizations every year. Subscribe for more on YouTube: https://tcrn.ch/youtube Follow TechCrunch on Instagram: http://tcrn.ch/instagram TikTok: https://tcrn.ch/tiktok X: tcrn.ch/x Threads: https://tcrn.ch/threads Facebook: https://tcrn.ch/facebook Bluesky: […]

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2024 Startup Battlefield Top 5 Finalists: Salva Health

Julieta is a portable, AI-powered breast cancer detection device that eliminates barriers to early screening, ensuring access even in remote areas. Subscribe for more on YouTube: https://tcrn.ch/youtube Follow TechCrunch on Instagram: http://tcrn.ch/instagram TikTok: https://tcrn.ch/tiktok X: tcrn.ch/x Threads: https://tcrn.ch/threads Facebook: https://tcrn.ch/facebook Bluesky: https://tcrn.ch/bluesky Mastodon: https://tcrn.ch/mstdn Read more: https://techcrunch.com/

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Archon emerges from stealth with $20M and ‘antibody cages’ to power up drug development

Archon Biosciences, a biotech startup putting AI to work designing novel biomolecules, has just emerged from stealth with an impressive $20 million in seed funding. The company aims to supercharge antibody treatments using specially designed protein “cages” that multiply their effects, opening up new opportunities in drug development. This is the first company to be […]

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