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AI Tool Reveals Long COVID May Affect 23% of People

This shows people.A new AI tool identified long COVID in 22.8% of patients, a much higher rate than previously diagnosed. By analyzing extensive health records from nearly 300,000 patients, the algorithm identifies long COVID by distinguishing symptoms linked specifically to SARS-CoV-2 infection rather than pre-existing conditions. This AI approach, known as "precision phenotyping," helps clinicians differentiate long COVID symptoms from other health issues and may improve diagnostic accuracy by about 3%.

Pathway Identified for Early Intervention in ALS Progression

This shows stem cells.Researchers have uncovered a mechanism that may trigger ALS’s earliest stages, identifying proteins that mislocalize, causing neuron degeneration. By targeting the RNA-binding protein SmD1, scientists were able to prevent key ALS proteins from leaving their protective cellular zones, preserving neuron function. The findings may lead to ALS therapies capable of halting progression before significant neurodegeneration occurs, offering potential new strategies against the disease.

Chimpanzees’ Task Performance Changes When Observed by Humans

This shows a chimp at a touch screen.A new study finds that chimpanzees, like humans, are affected by being watched: their performance on computer tasks improved on difficult tasks with larger human audiences but declined on simpler ones. This phenomenon, known as the "audience effect," was previously thought to be unique to humans and linked to reputation management. The results suggest that sensitivity to being observed may have evolved before human society developed its complex reputation-based social structures.

Insights on Brain Aging and Lifelong Cognitive Health

This shows a brain.A groundbreaking 25-year study has shown that childhood cognitive ability significantly impacts intelligence in older age, with nearly half of cognitive variance persisting across decades. The research tracked participants from childhood through their eighties, linking higher childhood intelligence to improved longevity. This study also revealed significant differences in brain aging, suggesting that genetics and early-life factors profoundly shape cognitive health.

Novel Vaccine Targets Deadly Brain Tumors with Precision

This shows a doctor looking at brain scans.A novel vaccine can mobilize the immune system to precisely target and attack cancerous brain tumors, specifically gliomas, one of the deadliest brain tumor types. This groundbreaking work demonstrates that the body’s immune system can be directed to target proteins with cancer-driving mutations in tumors, marking a significant advance in immunotherapy.

Newly Discovered Brain Neurons May Help Curb Hunger

This shows a brain.Scientists have uncovered a new neuron type, BNC2, which acts quickly to counter hunger-promoting neurons, potentially leading to more effective appetite regulation. These BNC2 neurons, located in the brain’s arcuate nucleus, respond rapidly to hunger cues by inhibiting AGRP neurons responsible for driving appetite. This discovery adds a crucial layer to our understanding of the neural circuits controlling hunger and opens the door for novel treatments for obesity and metabolic conditions.

How the Brain Reacts to Movie Scenes

This shows a brain on a movie screen.By analyzing fMRI scans of people watching films, neuroscientists have created a comprehensive functional map of the brain, showing how it activates in response to complex scenes. This study identified 24 distinct networks that process aspects like faces, speech, or movement, and revealed how executive functions shift between easy and challenging scenes.
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